SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48b0b062c6aa92ace0ba2bc4333a195137c0a6ca6edd0ced9990202656743777' 
  AND token = 'n8iWwx9GfV9dEbTJP4b3jaN/HDUoE9OknxSV33uCVoE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}