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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48ab8ece2e886805cafa2f05c82b6cacf3290e3a79d595d6987da9c6f2411bad' 
  AND token = 'Y8DMaDPBmMwQMhUYUDYC4YFbq0UHVn3oiaAsUt7+VYc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}