SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b53e27df66596ea4d17e8fd5bbc8e7d059628c4d6cad9e1ec2b1ec082151eef' 
  AND token = 'IjUyuQq/rrh4e22KmYyLs0NSjZy66IHeL/OhUvSe9a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}