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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8ca1a8b3d633e6b70afd699a017a20d75532414b278a738343fd0d7b9bd4a08' 
  AND token = 'q8NSu02yK9NnjB5zEehU+fqPkPMu9hfWRX+wclxu3mE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}