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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c74f4a1cbc77471f70bbd1aac6e40a23ae1adee8a1c52636a05fc8d11292deb' 
  AND token = 'gJ73QeifEqlky1FNxb/r7Z61Ij0rU2G9ETeD7AM5RG0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}