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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a819ee2eb583c5d18d5278149215e5f2e1dcc79fc34bec611054b35b072cbd9' 
  AND token = 'gsMHXyLFWXP0as2H/yz+NaCIjHwBXxkoM8vS/0AGYwA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}