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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25acf5380933feed026876bcffbd2d617dd5bcd9fc09738866dd2b1cb134e247' 
  AND token = 'HfkJqsiJ2CtmDgoDSFPdbtpPCCraxHA6Xdf0PvU/6Io=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}