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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'af4aace6c95371e70b150ae0053af2e81c7e9f613d2a110e062a80361b50267a' 
  AND token = 'SmoentAaNSRfCCGQobGdMtVXe2xBmLcwchNrt3lg+Rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}