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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48cfc4da8b42e18df57e1ccbe4d9b8f3918209860da00492e7b15054e3949dd5' 
  AND token = 'Akj0DgVZl8P+RH9KtdOXRXlOa6iB0x68W5h4P4h0ZCY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}