SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3803d435d84eba7d6b37508cf6dd95280bb6446fd64407051c3af38ab8dd072c' 
  AND token = 'DE2WvTvUTRNcwxnTecaAB0Juj2edUx3FA6hkKCkymMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}