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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09ebbeef68e1261a743baefdaf5b390b3ebcca291bda566754b5a7415325fab9' 
  AND token = 'wbmYDuhwEaUvzGbUNoXZb2Z2SQz2tvl4FHD73NF/NOI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}