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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4debb76df8acc50ab07b49b8421f56c71f93f80e3aac5fa0938ec14f03fdf69f' 
  AND token = 'VkyTPxZI4+FO3s1UJtmrZaPlWOYsyGZm8mEWb/rtUKU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}