SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae911676836ea80c817ec9f07ba2cdd314c4d41f5495cd255a9e4e99b2029ff2' 
  AND token = 'zqpOMmKW5PRh7nTaxw1pgyh7xMDZAF+BcoZc+oa8bVU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}