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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ca61584bd1a8b7658fb58ed96f13f93906e58e9ba7c38910bed72dac82ed619' 
  AND token = 'pdfV2/1PecIuDprApfhgnDn2e7TTE5Z8uivfYrrIWug=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}