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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '93ed40b1377bd4e06932044c850d4e89b05c6869df65e9d9e808144b357c3b05' 
  AND token = '4lgeLb1ET3Pq0KVN6ey4soN/+bxGa2Rg/qgP2kPTDMw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}