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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '456af39b6f757f7be0e13368986729659293c628da81de8c45af8dcaf78ab58a' 
  AND token = 'JuQUCS6YaLgrEoUhRE2nIC2VCx1wm7U8MNuXds2YLhU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}