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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f13260cc1e4019774c1916d81cca5a6b2421007d2fdcced1850c4ed1bcc9e3a5' 
  AND token = '8DdR1tIyYNYp/NlIc0z5+EfJt3rpgSlcmCwvZacvKAA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}