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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2cbadeba94a6491ae945d85c42f5516d5e5066b3b0881e552a942889ad43ab84' 
  AND token = 'p4CZjkLD0m9XxBrWH4oHsSanC47/mBVvKmgdHzAkgCg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}