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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7edc4805b72036e6924114487ba1cb883e6a0eb1cc65fb317c7b460f0dc11202' 
  AND token = 'HdbYE/IYECrFFoKHRPnRCxfqEchk7YYBmyBLBK3mdF8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}