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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b87a04b0ed5a6f09ce068a4833477e5150e2d35270b037e0e4b4a6e943836613' 
  AND token = 'R39Gqeuhf4RaN92duazDYpggs3aO2qBfPswJ79pgR3k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}