SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd980cc3eca6cc86c34a43e014cb35fca0be65d2f1e2d48d1efa2bd12b2fdd969' 
  AND token = '2dSK+xGI5veApht5EFEU9fyDtLv3rSk9z2TQjDhlyZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}