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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e44161dff2f7f6d7df61fd2ce13ed0449765a083de194cf250fcb45348f4324' 
  AND token = 'cztRoreysySHucBgTWFrjSMKZrJ6gpFQSrm3Vh6b/v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}