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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44c5fcae09f24843427d4f636380198f52a8a3329269b335fe967fc84e5857d1' 
  AND token = 'AAa3DeklFJ/kBbnHvdp9eLQXWZtpQF2hYccm7vKaxlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}