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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3e1b01006f44ad4cde30a7f4104dfabf511852e6d638592c2853b853012ef560' 
  AND token = 'LRDxiZNBtGlFFJDvPZoAYoQ1QZBBo2Zg0tvJiSdnaUQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}