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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7141f547acedf8be774ddc1fe418f1e50e37551cd9d6c0f3ff880d276ff2a596' 
  AND token = 'VT169N3qds4Q+RhBTTU5VRI0wA0/j4yHYBdHUFsl9RM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}