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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '188ded2014a46a6fd2151f17abeb9d3b786c691e1ccb82121b3725d4f962010c' 
  AND token = 's4pM4OhQyfdLBz4qWd+OxSnS3jdvof3NSR4O2yECRrQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}