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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'aa11fe58d110866367064d2ea7dcd163111681c5bf9fe4416d9714d6b6f11666' 
  AND token = 'Cu2jJfY09+hxy0mWFzQOxwnNPjK2YNYPudPMudgEQjQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}