SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100a65907310b5c928dc41081a953f2c4bcd0ad842f29825d5074f5bca6307ef' 
  AND token = 'vqyrYQV2RFeGFJyWbCTfgGdNxnil55+yRRs+6MZUHic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}