SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7b4e9b65eac5b4937b53cb0e8d6b865773b011d27fb4d7525a5a33f3ac5c0cb9' 
  AND token = 's6ptlQHnltjZeZV7xYSZMtKabsF4auS0PydXAtIf910=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}