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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '581e3951d2935aa16093115321f5cd6ff7e768ba6d7042cddcb9da6b6011851f' 
  AND token = 'h7sv5cHxAb8DDJZdkHtKSWexNlUkAMLdxyzMurY1nvg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}