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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e9648a8ffa71c739bf0fa776ba35e128839983b5453313cc573cf73d91ebb35' 
  AND token = 'ymcA1+sOx3jDHYGX42w4XxVRQu+6/i3/GRbHyM/s+a4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}