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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e82ffc7c0b29e22653aa66737f204c449704d15b414354321395c4419174496f' 
  AND token = 'RHShZZlSMOD9YHlvXE5quASDsTpFw6hIxl1kYTmWTB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}