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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e991e6f0f9a662b80cfb830dab2c06f4b8378a83f32163ad2a437d9eda90188f' 
  AND token = 'wC9cqG7Tu+pFIuQ/r3qDUpoB20sEhJij4HyKX0JipRE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}