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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '543cb637a1918a9e0ed92db54dcd1ea23e4db72c185700b2a98fe43de26e8d6d' 
  AND token = 'rqCxlxciXLemlfS8TC/QEvSnGtSauHe0XOFR9KrF4Ic=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}