SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b9fae69ae801c299d8f2cc8abc3bda8a6a4d0e7b15c0563c5cf3c18381768d' 
  AND token = 'VFqv6goP5uHO5dQRE8LrYzYyllC7dhOGlq3jvx0urJE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}