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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd49616c67b0e9422d537037ddb730ae42a584cf972c199b6e092239f9c987691' 
  AND token = 'b30keSI3tTAA4EjRFXzyDmPpnYb3DoX66uRlNMxFXXs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}