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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e516b4260df2859d8d69b3cb7c90c4e4c8c3760a77680ff6c0def8681b3779d4' 
  AND token = 'wSXxMvqXptbxgZRtLB528wKmB7WAetuc4dXvBBMBDgs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}