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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8b2d771ef83edf5bd9329ee91f35d1e7a6ec4be32b3601da47dee53e3113683a' 
  AND token = 'rAIA+3xYgVj+Cx7i8XmwTlPzPRbpLXxRnTsr0rmzlY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}