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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e1482f3b0af741a7c071b16370a03ec8e7688539d0b2f7233e1e4f1206020c' 
  AND token = 'Bbn6MVBz7+9kjhbyuCfpC6Y6QUJpk9A9ufuc2Ojnawg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}