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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '559aa2a26d79097f22fb1ac43618f9f1d202b056f996cced6c671ddc4be40560' 
  AND token = 'ewh2P2QvNT3hn+WJ8wQsYz6BY/4x4bB/w0cR4qxxSTA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}