SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d426ca43bd2099dcb57069d76bcc39216632ed85b272eb96c78971a6084d424' 
  AND token = 'JY1DLs3aF1WKjzY7hKGlclEeVSwIE6jvkF1JNaeyyE8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}