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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '354dd29c84708d4ddb69e19cadc2d76dd81d5d0a3f0def8b5729f8be75eee812' 
  AND token = 'p++ssAbSYNO3H0dGGuSmj9+9s03HenxjcH8JR+WQqJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}