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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ad9aa0d04bfe56c2302ac7e8242293369d6e30f5c516616333f082f1cc64f1b3' 
  AND token = 'D43M/xFVQd+wQdwVOAYkuhMCbz21HUP8MI0+fopI5MY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}