SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7b1f2906e3be4a33e16bd841e244d9d8f035090f9b2ff02f58a2f705e314592' 
  AND token = 'l69XZmdf2gvaP9sdYdmCHPF8VxX3fTcEpVE6lC8sEJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}