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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '66a0265d42c1be1655ad168b7b31acc6b6d66291c03be21a59a83a0649ff6aad' 
  AND token = 'rKoPnbPYpvKwfxXL4VEsQRQ9Cu2GeZdsLR0/uHwdi9g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}