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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ed2a29ce36edf571a1cdefd9ec1caa09265f9d0466b0072573a4d37c8eabf6e' 
  AND token = '4+UPrdkJLp1R3Gn0WcGEVlJsfY/XPDcyQfL8u5F78jg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}