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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6c46e49f1056fb443c7416746b44c1712fb31a131f376505cbb34229acb8787' 
  AND token = 'd+pv63ENGmqKgDyPCCa5Dej41CS5bt/SfDBZiHChY4M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}