SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '777d1e02b1440831ef68de1e7a13421eb0021ec927745ace665d85a8ebf34daa' 
  AND token = '1vGQIaTn04P9q1pZtcvJzOiH9z2mkdI9Dj4h9UflHsQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}