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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4f0c3582d724dd696503a46318a6ba89d703b0fc66398e998b37be4bb1712aab' 
  AND token = 'u1PUCAmxR8YW9BBOScIpzotCQ+W6hcm0LUUgyH9XPak=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}