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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6e4692fd15396d3e771241014997a4c0bf12ac73c83f100b644121da78008903' 
  AND token = 'kFTWL359AzpdQl+w1AoUD4hp9IwvF68jJEhOr5TEdtE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}